Useful Resources

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Background/Epidemiology

• Tableau Public

• Nosocomial Spread

• Epidemic Calculator

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Signs and Symptoms

• Dermatologic

• Cardiovascular Disease (JAMA Cardiology)

• Patient characteristics in 1099 patients in China (NEJM)

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Prognostication markers (lab findings, comorbidities, imaging findings)

• Hypertension and diabetes associated with worse outcomes

• Wuhan meta-analysis

  • N = 46,248​

  • Most severe disease: HTN (OR 2.4), Respiratory disease (OR - 2.46), CVD (OR -3.42)

  • Not corrected for age, SES, smoking

• Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study

  • On average 17 yrs older (age 68 vs 51)

  • HTN 48% vs 24%; T2DM/ CVD/ COPD more common too

  • Dyspnea 62% vs 31%

  • Lymphpenia 91% vs 47%

  • ALT, AST, Cr, CK, LDH, TnI, BNP, D-dimer higher in deceased

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Guidelines for home management of patients 

• BMJ Clinical guide for physicians providing virtual care

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PPE Guidelines

• JAMA Insights

  • ​Study suggesting surgical masks may not be enough for cough/sneezes

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CoVID-specific therapies

• A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19

  • ​Lopinavir-negative trial 

• Early antiviral treatment contributes to alleviate the severity and improve the prognosis of patients with novel coronavirus disease (COVID-19).

• Convalescent plasma

• COVID-19: consider cytokine storm syndromes and immunosuppression

  • Theory of HLH Response (immunosuppression beneficial?)

• IVIG

• Toronto Guidelines

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ICU Guidelines on Management of Respiratory Failure/ARDS

• Outcomes in ICU in Washington (n=21)

• Management of critically unwell patients in CoVID (Surviving sepsis group)

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Safe Intubation/Safe Code Blues

• Airways

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ACE/ARBs

• Angiotensin Converting Enzyme 2: A Double-Edged Sword

• COVID-19 and Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers

• Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

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NSAIDs

• Non-steroidal anti-inflammatory drugs and covid-19

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Patients with CVD

• Coronavirus Disease 2019 (COVID-19) and Cardiovascular Disease

• CCS COVID-19 Rapid Response Team

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Patients with Autoimmune Conditions

• COVID-19 AND IBD

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Patients with Diabetes

• Commentary: COVID-19 in Patients with Diabetes

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Pregnant Patients

• Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn

• Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records​​

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Pediatric Patients

• Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China

• Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study

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Resource Allocation Guidelines

• Fair Allocation of Scarce Medical Resources in the Time of Covid-19

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Additional Resources

• CoVID Physician Group

• CoVID papers/ research

  • https://ucsf.app.box.com/s/2laxq0v00zg2ope9jppsqtnv1mtxd52z

  • LitCOVID - https://www.ncbi.nlm.nih.gov/research/coronavirus/

  • https://www.cebm.net/oxford-covid-19/

  • https://covid19central.ca/

• ICU specific educational resources

  • https://www.covidprotocols.org/

  • https://www.cochranelibrary.com/collections/doi/SC000039/full

  • https://covidcriticalcare.ca/

  • https://www.quickicutraining.com/

  • http://www.emergentc.ca/

• Community resources

  • Covid Resources for GTA Muslim Community

  • Covid with Kids - "Home sequestration, home schooling, and staying sane"

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