NSAIDs 

Version 1: 19-03-2020

NSAID use in CoVID

There has been speculation based on reports from France that in four young patients with coronavirus, NSAID use was associated with worse outcomes. They back this with some studies showing that NSAID use is associated with worse pulmonary infections in general. We also know that NSAIDs can have harmful effects on our renal and cardiovascular function (prolonged use).

https://www.bmj.com/content/bmj/368/bmj.m1086.full.pdf

 

On the contrary, there is old data from SaRS CoV to suggest that perhaps NSAID use is important to inhibit coronavirus replication in-vitro

https://www.ncbi.nlm.nih.gov/pubmed/17302372

 

On the whole, there is NOT enough evidence to advise for or against the use of NSAIDs. As is clinical practice commonly, acetaminophen is safe to be used in fevers and generally has less side effects than non-steroidal anti-inflammatory drugs.

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